Strong, beautiful, fearless, multi-tasking, loving, caring is how we would describe a woman. A hand that rocks the cradle, rules the world. Of all the rights of a woman, one of the greatest is to become a mother. But what happens, when she starts neglecting her own health by prioritizing other things by listing them ahead of her health?
The prevalence of vitamin D insufficiency nearly doubled from 1994 to 2004. Amongst women of reproductive age, more than 40 percent are insufficient in vitamin D.
According to USC Fertility, the significance of vitamin D – about how it affects the reproductive system was exhibited carrying out the experiments with mice. Vitamin D deficient mice were studied, which demonstrated underdevelopment of the uterus and inability to form normal mature eggs, which resulted in infertility. Further, it was observed that if such mice were able to achieve pregnancy, their foetuses showed impairment in growth. Such problems were controlled and their condition was regulated with the Vitamin D supplementation. It was further studied that not alone calcium, but Vitamin D plays a crucial role in reproduction as the Vitamin helps the body in absorbing calcium.
Vitamin D receptor is present in human female organs like ovary, uterus and placenta and the active form of Vitamin D, Calcitriol has many significant roles in the human reproductive system. When Calcitriol binds with the receptor on the surface of human reproductive organs, it is able to regulate the genes responsible for the making of Estrogen hormone.
The uterine lining is responsible for producing calcitriol in response to the embryo as it enters the uterine cavity, shortly before implantation. This active form of Vitamin D is responsible for regulating several genes involved in embryo implantation. Once a woman becomes pregnant, the uterus and placenta continue to make calcitriol, which helps organize immune cells in the uterus, so that infections can be fought without harming the pregnancy.
Poor vitamin D status has been associated with certain pregnancy complications such as gestational hypertension and diabetes.
Vitamin D deficiency is linked to reduced pregnancy rates according to the recent data published in “The Journal of Clinical Endocrinology & Metabolism”.
Another research study carried out by Alessio Paffoni of the Ospedale Maggiore Policlinico in Italy, stated in a press release that their work was the largest study till date to examine how vitamin D affected fertility in women who were undergoing in vitro fertilization.
Paffoni and his associates assessed 154 women who were vitamin D deficient (<20 ng/mL) and 181 women with sufficient vitamin D levels (≥20 ng/mL) to determine the effect of levels on fertility.
They found that women who had adequate levels of vitamin D were more likely to produce high-quality embryos owing to the sufficient vitamin D levels linked to the quality of eggs in the ovaries. Such women were more likely to become pregnant than women who were deficient in vitamin D.
Participants were also divided into deficient, insufficient (21 ng/mL-29 ng/mL) and sufficient (≥30 ng/mL) levels of vitamin D groups, and researchers found increasing rates of pregnancy with increasing levels of Vitamin D.
Their research thus suggested that low levels of vitamin D contributed to infertility, Paffoni said.